CORRELATION OF SHEAR WAVE ELASTOGRAPHY VALUES WITH SONOGRAPHIC GRADES OF FATTY LIVER DISEASE

Abstract

Background: The Non-alcoholic fatty liver disease (NAFLD) is the gathering of fat in the liver without any unnecessary liquor utilization or other known liver pathologies .1 Non-alcoholic fatty liver disease is more normal in the western world, with a commonness of 19-46% in the overall US population. Objective: To evaluate and correlate shear wave Elastography values with Sonographic grades of fatty liver disease Material and Methods: In this research, an Analytical-cross sectional approach was adopted at PKLI, Lahore for four months. A total of 125 patients were included in this study. Data was collected by using Questionnaire/Performa. A non-convenient sampling technique was used in this study. Data was evaluated and analyzed with statistical package for social sciences (SPSS) v-25 and Microsoft excel.

Results: A total of 125 patients were recruited in this study. Out of which 52(41.6%) were male and 73(58.4%) were female patients with mean age of 44.25 ± 13.245. In this study, the most common grade after on gray scale USG was Grade 1 (36%), followed by Grade 2 in (28%), Grade 0 in (25.6%) patients and least common was grade 3 in (10%) patients. On assessment of these 125 patients by shear wave Elastography, the mean subcutaneous liver thickness was found to be 0.86 ± 0.928 cap. By shear wave Elastography the most common grade found was Grade 0 in 41.6% patients followed by Grade 1 in 39.2%, Grade 2 in 10.4% and Grade 3 in only 8.8%. There was a significant correlation with correlation coefficient of 0.63 (p value <0.01), between gray scale sonographic grades of fatty liver and tissue thickness on shear wave Elastography.

Conclusion: This study concluded that study population (mean age: 44.25 ± 13.245) shows increased frequency (58.4%) of female patients. Also, Grade 1 was the most common Grade on grey scale sonographic assessment and Grade 0 was the commonest on shear wave elastogrphic assessment. There was also a significant correlation was found between gray scale sonographic grades of fatty liver and tissue thickness on shear wave Elastography with correlation coefficient of 0.63 (p value <0.01)