Frontier in Medical & Health Research
Vol. 2 No. 3 (2024), Articles
Vol. 2 No. 3 (2024)

FREQUENCY OF MATERNAL MORTALITY IN PATIENTS OF PRE-ECLAMPSIA/OR ECLAMPSIA AT A TERTIARY CARE CENTRE

Articles
Published 2024-07-31
  • Dr. Tamkeen Zehra
  • Dr. Erum Majid Shaikh
  • Dr. Ume Qulsoom
  • Dr. Fatima Nasir
  • Dr. Simrun
Dr. Tamkeen Zehra
Dr. Erum Majid Shaikh
Dr. Ume Qulsoom
Dr. Fatima Nasir
Dr. Simrun
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Keywords

Pre-eclampsia, Eclampsia, Maternal mortality, Hypertensive disorders of pregnancy, HELLP syndrome

How to Cite

FREQUENCY OF MATERNAL MORTALITY IN PATIENTS OF PRE-ECLAMPSIA/OR ECLAMPSIA AT A TERTIARY CARE CENTRE. (2024). Frontier in Medical and Health Research, 2(3), 61-67. https://fmhr.net/index.php/fmhr/article/view/3789
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Abstract

Objective: To determine the frequency of maternal mortality in patients diagnosed with pre-eclampsia and eclampsia at a tertiary care hospital.

Study Design: Cross-sectional study.

Place and Duration of Study: Department of Gynaecology and Obstetrics, Jinnah Postgraduate Medical Centre (JPMC), Karachi, from June 2023 to June 2024

Methodology: A total of 196 pregnant women aged 18–45 years diagnosed with pre-eclampsia or eclampsia were included through non-probability consecutive sampling. Data were collected using a structured proforma documenting demographic characteristics, clinical parameters, laboratory findings, maternal complications, fetal outcomes, and final maternal outcome at discharge. Data were analysed using SPSS version 22.

Results: The mean age was 31.4 ± 8.0 years and mean gestational age was 34.1 ± 3.5 weeks. Maternal mortality was observed in 29 (14.8%) patients. Mortality was higher in severe pre-eclampsia (16.2%) and eclampsia (15.4%) compared to mild pre-eclampsia (12.1%), though the association was not statistically significant (p=0.438). Booking status (p=1.000) and residence (p=0.493) were also not significantly associated with mortality. Common maternal complications included obstetric hemorrhage (50.0%), renal failure (44.9%), pulmonary edema (34.2%), and HELLP syndrome (23.5%). Mean birth weight was 2.49 ± 0.73 kg, and 46.9% of neonates required NICU admission.

Conclusion: Pre-eclampsia and eclampsia remain major contributors to maternal mortality in tertiary care settings. Early detection, timely intervention, and strengthening of referral and critical care systems are essential to reduce preventable maternal deaths.

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