Abstract
Background:
Hyperpigmentation is defined as darkened areas of the skin created by excess pigment, where the opposite would apply, too little pigment leads to a lighter-colored skin.
Objectives:
The objective of the study was to compare Trichloroacetic Acid (TCA) peel versus glycolic acid Peel for the treatment of hyperpigmentation.
Methodology:
Data was be collected from dermatology/aesthetic clinic patients after informed consent using a pre-tested structured questionnaire covering demographics, clinical history, treatment details, and outcomes. Baseline assessment included MASI scoring and standardized facial photography, followed by 1–4 month follow-up evaluations. Outcomes include change in MASI score, clinical improvement, patient satisfaction, and adverse effects of glycolic acid vs TCA peels.
Results:
TCA peel and glycolic acid peels were all highly effective with significant hyperpigmentation reduction. Mean overall MASI score decreased from 14.07 to 7.68 (p<0.001). TCA peel was significantly better with lower post-treatment MASI score of 6.37 versus 9.00 with glycolic acid peel (p<0.01). Both peels were effective and patients were 95% very satisfied.
Conclusion:
Both trichloroacetic acid (TCA) and glycolic acid peels were effective in reducing hyperpigmentation, with a significant improvement in MASI scores. TCA peel demonstrated superior efficacy compared to glycolic acid but was associated with more moderate to severe side effects