BETA-THALASSEMIA: CURRENT PERSPECTIVES ON PATHOGENESIS, SCREENING, AND TREATMENT

Abstract

Beta thalassemia represents one of the maximum not unusual and severe inherited blood disorders affecting the population of Pakistan. The disorder burden is intensified by way of an excessive prevalence of providers, massive consanguineous marital practices, and barriers in organized screening and healthcare offerings as an end result Pakistan stories a great medical, social, and financial effect from both transfusion established and non-transfusion sorts of beta thalassemia. This review brings collectively modern day know how on ailment distribution, genetic mechanisms, clinical manifestations, diagnostic strategies, treatment alternatives, preventive techniques, healthcare gadget limitations, and sensible hints that are applicable to the countrywide healthcare putting of Pakistan.