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Abstract
Streptomyces griseus is a beneficial and well-known actinobacterium that produces various types of bioactive metabolites. This work investigates the antibacterial, antidiabetic and anti-inflammatory potential of Streptomyces griseus to explore its therapeutic potential. The crude extract of this bacterium was evaluated for antibacterial potential against selected pathogenic bacteria. The anti-inflammatory potential was measured through protein denaturation assay. Further, the antidiabetic potential was observed using an amylase inhibitory assay. The findings demonstrated considerable antibacterial potential against tested bacterial strains and also showed notable anti-inflammatory potential by reducing protein denaturation. Moreover, this bacterium showed a promising antidiabetic effect through the inhibition of carbohydrate-hydrolyzing enzymes. Overall, these outcomes showed that Streptomyces griseus is a beneficial source of bioactive metabolites with multifunctional therapeutic applications. This bacterium could arise as an auspicious candidate for the production of novel natural bioactive compounds.