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Abstract
Background:
Ischemic heart disease is one of the major causes of mortality and disability worldwide. CABG is the definitive surgical treatment to relieve symptoms and to improve survival of the patients. Aortic cross clamping is the pivotal step of the surgery in which aorta is deliberately occluded, thus temporarily halting the systemic blood flow. Cross clamp time (CCT) is regarded as the important factor that can influence patient’s postoperative outcomes.
Aim of the study:
To determine the impact of cross clamp time on postoperative mechanical ventilation duration and inotropic support requirements in CABG patients.
Methodology:
This comparative cross-sectional study was conducted at Cardiac Surgery Department of Punjab Institute of Cardiology, Lahore. This study included 100 patients undergoing CABG with CPB. Independent t test and chi square test were used to investigate associations.
Results:
A total of 100 patients were included, out of which 85 (85%) were male patients. The mean age (years), height (cm) and weight (kg) were 54.86 ± 9.48 years; 165.94 ± 8.76 and 72.32 ± 2.76, respectively. Baseline risk factors were comparable between groups with their non-significant p-values. The difference in mean aortic cross clamp time between the two groups was significant (38.10 ± 7.03 vs. 66.98 ± 12.90 minutes) p<0.001. No significant difference was observed in postoperative ejection fraction between both groups (p=0.47). However, prolonged CC time was significantly associated with increased postoperative inotropic support (p=0.04), without a corresponding increase in mechanical ventilation duration (p=0.71).
Conclusion:
Our study concluded that prolonged cross clamp time correlates with the increased need of inotropic support postoperatively. However, it does not result in increased demand for mechanical ventilation support.