Abstract
Background: High cholesterol and HDL levels, or hyperlipidemia, raise the risk of cardiovascular disease, particularly in people between the ages of 40 and 75 who also have comorbid diseases or consume a lot of fat. Cardiovascular disease and atherosclerosis are brought on by high lipid levels.
Objective: Investigating the various symptoms, diagnosis, and modern treatment options for hyperlipidemia is the aim of this comprehensive analysis. It will specifically look at how novel therapeutic medications, such as PCSK9 inhibitors, work and emphasize how important lifestyle modifications are to both treating and preventing this disease.
Methodology: This review looks at the pathogenesis, etiology, epidemiology, diagnosis, and therapeutic management of hyperlipidemia. It focuses on various lipoprotein types, lipid metabolism mechanisms, measurement methods, risk assessment, medication therapies, and lifestyle changes.
Conclusion: Hyperlipidemia is a risk factor for cardiovascular diseases that requires lifestyle modifications and early detection. Pharmacological therapy, such as PCSK9 inhibitors and statins, which target environmental factors, genetic predispositions, and LDL-c lowering, should be used as part of treatment to prevent major health problems