COMPARISON OF MATERNAL HYPOTENSION OF TWO DIFFERENT DOSES (12MG AND 15MG) OF 0.75% BUPIVACAINE SPINAL ANESTHESIA IN C-SECTION AT AIMS HOSPITAL MUZAFFARABAD

Abstract

This is a summary of a study conducted at Aims Muzaffarabad AJK from April 2024 to Sep 2024, which compared the effects of two different doses of bupivacaine (12mg and 15mg) on maternal hypotension after spinal anesthesia in patients undergoing elective cesarean section. The study found that 16% of patients in Group A (12mg bupivacaine) experienced hypotension 24 % of patients in Group B (15mg bupivacaine) experienced hypotension. We also compared other complications such as bradycardia, respiratory depression, nausea/vomiting, and patient irritation. The study concludes that a spinal dose of 12mg bupivacaine causes less maternal hypotension compared to 15mg, and these findings can help prevent significant hypotension in patients undergoing elective cesarean section under spinal anesthesia, as well as avoid harmful medications like volume overload and vasopressors for correction of drug-induced hypotension.

Here is a breakdown of the study:

Study design: Experimental study

Sample size: 100 patients (50 in each group)

Inclusion criteria: Patients between 20-45 years, ASA physical status I & II, undergoing elective cesarean section, intervertebral Space L3, L4.

Intervention: Spinal anesthesia with 12mg or 15mg bupivacaine

Outcome measure: Frequency of maternal hypotension

Results: Less hypotension in Group A (12mg) compared to Group B (15mg)

This study contributes to the existing literature on optimizing spinal anesthesia for cesarean sections while minimizing maternal hypotension.