CORRELATION BETWEEN PROSTATE VOLUME AND SEVERITY OF LOWER URINARY TRACT SYMPTOMS AMONG DIABETIC PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA

Abstract

Background: Benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) are prevalent urological conditions in aging men. Diabetes mellitus (DM) further impacts urological health through neuromuscular effects on the bladder. This study investigates the correlation between prostate volume (PV) and LUTS severity in diabetic men to strengthen evidence-based clinical management. Objectives: To evaluate the correlation between prostate volume and LUTS severity, assessed via the International Prostate Symptom Score (IPSS), among diabetic patients with BPH. Material and Methods: A prospective cross-sectional study was conducted on 138 diabetic BPH patients (aged ≥40 years) presenting with LUTS for abdominopelvic ultrasound. Demographic and clinical data (age, PV, diabetes duration) were collected via a structured questionnaire. LUTS severity was assessed using the IPSS (mild: 0–7, moderate: 8–19, severe: 20–35) along with a Quality of Life (QoL) single-item score (1–7). PV was measured via transabdominal ultrasonography using the standard ellipsoid formula. Statistical analyses included Pearson's correlation coefficient, Chi-Square, and One-Way ANOVA. Results: A significant moderate positive correlation was observed between PV and total IPSS (r = 0.513, p < 0.01). Furthermore, longer duration of diabetes was significantly associated with greater PV (p < 0.01) and heightened LUTS severity (p < 0.01). Conclusion: Prostatic enlargement significantly influences LUTS severity in diabetic BPH patients (r = 0.513). Prolonged diabetes duration exacerbates both prostate enlargement and symptom severity, emphasizing the need for concurrent glycemic and urological evaluation.