Abstract
Malaria remains one of the most significant vector-borne infectious diseases worldwide and continues to pose a major public health challenge, particularly in tropical and subtropical regions. The disease is caused by Plasmodium parasites and is transmitted to humans through the bite of infected female Anopheles mosquitoes. Despite considerable progress in malaria control programs, the disease remains endemic in many developing countries, including Pakistan, where it contributes substantially to morbidity and places a burden on healthcare services. The present study was conducted to determine the prevalence of malaria among patients visiting the District Hospital Mardan, Khyber Pakhtunkhwa, Pakistan. A total of 420 patient records were collected and analysed to assess the occurrence of malaria infection. The findings revealed that 113 patients (26.9%) were diagnosed with malaria, indicating a considerable disease burden in the study population. The observed prevalence highlights the continued transmission of malaria in the region and emphasizes the need for effective surveillance and control measures. The study underscores the importance of preventive strategies to reduce malaria transmission. These include the use of insecticide-treated mosquito nets, application of mosquito repellents, environmental management to reduce mosquito breeding sites, and increased public awareness regarding malaria prevention. Early diagnosis and prompt treatment remain essential for reducing disease complications and transmission. Antimalarial drugs such as chloroquine and primaquine continue to play an important role in the management of susceptible malaria cases. In conclusion, malaria remains a significant public health concern in District Mardan. Strengthening preventive measures, improving community awareness, and ensuring timely diagnosis and treatment are critical steps towards reducing the prevalence and impact of malaria in the region.