Abstract
Background:
Periorbital hyperpigmentation (POH) represents an important problem in aesthetic medicine due to its diverse etiology, which may include both genetics, vasculature problems, and lifestyle-related factors. Recently, there has been increased interest in the use of microneedling in combination with other procedures, such as PRP and hyaluronic acid serum application, aimed at increasing skin rejuvenation effects.
Objective:
To analyse and compare the effectiveness and safety of microneedling with platelet-rich plasma versus microneedling with hyaluronic acid serum in treating periorbital hyperpigmentation.
Methodology:
The study was conducted on 30 patients who were clinically diagnosed with POH. Patients were randomized that received either microneedling with PRP or microneedling with hyaluronic acid serum. Assessments were performed with the help of clinically approved scales, ceroscopy data, and patient satisfaction reports.
Results:
Positive results were noted in both treatment regimens. Microneedling combined with PRP demonstrated significantly better results related to pigment reduction and skin rejuvenation, whereas the second group reported only positive changes in hydration levels and minor reduction of pigmentation.
Conclusion:
It seems that microneedling along with PRP is more effective for the treatment of periorbital hyperpigmentation, whereas microneedling with HA serum serves as an additional alternative treatment. Both treatments proved to be safe for use.