FREQUENCY OF SURGICAL SITE INFECTION AND ANTIMICROBIAL SENSITIVITY PATTERN OF BACTERIAS ISOLATED IN ABDOMINAL SURGERIES IN OBSTETRICS AND GYNAE POPULATION

Abstract

Objective: This study aims to evaluate the frequency of surgical site infections, to determine the antimicrobial sensitivity pattern of microbial pathogens isolated in abdominal surgeries in the obstetrics and gynecology department post-surgery, and to study the predictors and risk factors of SSIs.

Methods: This is a prospective cross-sectional study. The approval for the study was taken from the IRB of Jinnah Postgraduate Medical Center Karachi. A total no of patients who had undergone abdominal surgical procedures (laparotomy, Caesarean section, also termed as C-section, and abdominal hysterectomy) were included in this study.  The outpatient or ambulatory were excluded. Vaginal, laproscopic and minimal incision surgeries (tube ligation), were not included in the study. The frequencies were measure through SPSS 27.

Results: We have observed 1304 procedures, of them emergency caesarian sections were 1151, elective CS were 51, 38 hysterectomies and laparotomies 64. The SSI was reported in 225 (17.2%) patients. The data was taken from patients who had developed SSI. Among culture-positive samples, methicillin-resistant Staphylococcus aureus (MRSA) was isolated in 42 cases (18.9%), Escherichia coli in 33 cases (14.9%), Pseudomonas species in 30 cases (13.5%), Acinetobacter species in 18 cases (8.1%), Klebsiella oxytoca in 9 cases (4.1%), Proteus species in 6 cases (2.7%), Staphylococcus aureus in 3 cases (1.4%), and Moraxella morganii in 3 cases (1.4%).

Conclusion: In conclusion, this study emphasizes that SSIs remain a significant postoperative complication, particularly following emergency procedures. The predominance of multidrug-resistant organisms reinforces the need for robust infection control practices, rational antibiotic use, and regular surveillance of local antimicrobial resistance patterns.