Frontier in Medical & Health Research
ANALYZING THE ROLE OF PERIOPERATIVE DEXAMETHASONE IN REDUCING THE RISK OF PONV IN PATIENTS UNDERGOING CAESAREAN SECTION UNDER SPINAL ANESTHESIA
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Keywords

ANALYZING THE ROLE
OF PERIOPERATIVE DEXAMETHASONE
IN REDUCING THE RISK
OF PONV IN PATIENTS
UNDERGOING CAESAREAN SECTION
UNDER SPINAL ANESTHESIA

How to Cite

ANALYZING THE ROLE OF PERIOPERATIVE DEXAMETHASONE IN REDUCING THE RISK OF PONV IN PATIENTS UNDERGOING CAESAREAN SECTION UNDER SPINAL ANESTHESIA. (2026). Frontier in Medical and Health Research, 4(1), 705-713. https://fmhr.net/index.php/fmhr/article/view/2126

Abstract

Background: PONV, or Postoperative nausea and vomiting is common and distressing side effect after caesarean section under spinal anesthesia, affecting maternal comfort, recovery, and satisfaction. Dexamethasone, a corticosteroid with proven antiemetic and analgesic properties, has been studied as a prophylactic agent in various surgeries. However, its role in reducing PONV specifically in obstetric patients undergoing caesarean section remains an area of clinical interest.

Objective: The primary goal of the trial was to ascertain how well single-dose dexamethasone reduced PONV.

Methodology: Ganga Ram Hospital Lahore provided data after the acceptance of the summary.  Data for this research came from a questionnaire that asked participants about their experiences with analyzing the role of perioperative dexamethasone helps to reduce the chance of PONV in persons with caesarean section performed under spinal anesthesia. The goals of the research and the procedures for obtaining participants' agreement were outlined in the first steps.

Results: The study included 60 women under spinal anesthesia having a cesarean section, separated equally into dexamethasone and saline groups. The dexamethasone the group had a significantly decreased incidence of vomiting within 24 hours (13.3%) than the saline group (33.3%), and the mean vomiting episodes were fewer (0.3 vs 0.8). Requirement of rescue ondansetron was also reduced (16.7% vs 36.7%). Additionally, total analgesic dose and rescue analgesia requirement were lower in the dexamethasone group, indicating better pain control. Overall, dexamethasone improved both PONV outcomes and analgesic requirements.

Conclusion: Perioperative administration of dexamethasone (8 mg IV) considerably Reduced the incidence and frequency of postoperative vomiting, as well as the requirement for rescue antiemetics in women following caesarean section under spinal anesthesia. It also showed a trend toward reduced analgesic requirements. Dexamethasone is therefore a safe, effective, and economical option for improving maternal comfort and recovery.

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