Abstract
Background:
In areas where pesticides are widely used, such as agriculture, organophosphate poisoning is still a major public health risk. If not treated quickly and efficiently, it is linked to high rates of morbidity and mortality.
Objective:
This study aims to identify clinical and laboratory prognostic markers in patients with organophosphorus (OP) poisoning and to assess their association with key outcomes, including hospital stay, ICU admission, and mortality. The findings are intended to guide the development of evidence-based recommendations for early risk assessment and triage in OP poisoning cases.
Method:
A total of 109 patients who had been diagnosed with organophosphate toxicity participated in prospective observational research. Descriptive and inferential statistics were used to gather and analyze data on outcome, clinical presentation, exposure intent, treatment methods, and demographics.
Results:
This study examined 109 poisoning cases in all. All of the instances were reported from Peshawar, and the patients were mostly young and female. Students and housewives were the occupational groups most impacted, and the majority of exposures were purposeful (suicidal). In the majority of instances, prompt hospitalization and adherence to prescribed treatment plans had positive short-term clinical results.
Treatment:
The cornerstone of treatment was standardized atropine and pralidoxime administration, which was complemented by supportive care, such as ventilator support when necessary, and produced positive results.