Frontier in Medical & Health Research
HEREDITARY BREAST CANCER: UNRAVELING THE GENETIC LINK BETWEEN GENERATIONS
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Keywords

Breast Cancer, Hereditary inheritance, BRCA1, BRCA2, Genetic susceptibility, Mutations in genes, Ancestry, Genetic guidance

How to Cite

HEREDITARY BREAST CANCER: UNRAVELING THE GENETIC LINK BETWEEN GENERATIONS. (2025). Frontier in Medical and Health Research, 3(10), 1516-1523. https://fmhr.net/index.php/fmhr/article/view/1895

Abstract

Breast cancer is very dangerous and harmful cancer at international level that harm Both the sexes. Many cases of cancer result from environmental, hormonal, or lifestyle influences, a notable portion steps from inherited genetic changes. Replacement in genes like BRCA 1, BRC A2, TP53, and PALB2 Can greatly heighten the chances of forming breast or egg producing cancer within families. Still, having such changes only raise exposure it does not confirm that cancer will develop through genetic testing and support, individuals at high level risk can be noted in early, allowing for timely preemptive and handling strategies. Precautions, including prevantive surgery, risk-reducing medications, healthier lifestyle choices, and daily base screenings, can notably lower the chance of cancer in mutational carriers. However, most breast cancer cases around 85-90% occur in individuals with no genetic history, indicating that environmental and lifestyle are responsible for the majority of incidences. While inherited mutations can transmit risk from one generation to the next, most cases are non-genetic. Therefore, the patient of breast cancer control relies on a combination of prevention, early detection, and personalized treatment that takes into account both genetic and environmental contributions.

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