Frontier in Medical & Health Research
Vol. 3 No. 7 (2025), Articles
Vol. 3 No. 7 (2025)

ASSOCIATION OF THE AMNIOTIC FLUID INDEX (AFI) WITH ADVERSE PERINATAL FETAL AND MATERNAL OUTCOMES IN PREGNANCIES COMPLICATED BY PRETERM PREMATURE RUPTURE OF MEMBRANES (PPROM)

Articles
Published 2025-09-02
  • Dr Tehreem Fatima
  • Dr Safia Perveen
  • Dr Suleman Azhar
  • Dr Tuba Mehmood
  • Dr Ammar Ali
Dr Tehreem Fatima
Dr Safia Perveen
Dr Suleman Azhar
Dr Tuba Mehmood
Dr Ammar Ali
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Keywords

Amniotic fluid index, PPROM, preterm birth, perinatal outcome, chorioamnionitis

How to Cite

ASSOCIATION OF THE AMNIOTIC FLUID INDEX (AFI) WITH ADVERSE PERINATAL FETAL AND MATERNAL OUTCOMES IN PREGNANCIES COMPLICATED BY PRETERM PREMATURE RUPTURE OF MEMBRANES (PPROM). (2025). Frontier in Medical and Health Research, 3(7), 1502-1509. https://fmhr.net/index.php/fmhr/article/view/1559
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Abstract

Background: Preterm premature rupture of membranes (PPROM) is a significant obstetric complication contributing to preterm birth and adverse perinatal outcomes.

Objective: To determine the association of amniotic fluid index (AFI) with adverse perinatal and maternal outcomes in pregnancies complicated by PPROM.

Methodology: This prospective cohort study was conducted at the Department of Obstetrics and Gynecology, Sahiwal Teaching Hospital, Sahiwal, from March 2025 to June 2025, on 60 women diagnosed with PPROM. Participants were divided into two groups: AFI < 5 cm (n = 30) and AFI ≥ 5 cm (n = 30). Data on maternal and neonatal outcomes, including cesarean delivery, chorioamnionitis, birth weight, NICU admission, respiratory distress syndrome (RDS), and Apgar score <7 at 5 minutes, were recorded.

Results: The mean birth weight was significantly lower in the AFI < 5 cm group (1455.2 ± 325.6 g) compared to the AFI ≥ 5 cm group (1618.9 ± 285.4 g; p = 0.03). Low Apgar scores (<7 at 5 minutes) were more frequent in the low AFI group (46.7% vs. 20.0%; p = 0.04). RDS (40.0% vs. 16.7%; p = 0.05) and NICU admissions (53.3% vs. 30.0%; p = 0.07) were also more common among low AFI cases. Maternal complications, including cesarean delivery (56.7% vs. 33.3%) and chorioamnionitis (33.3% vs. 13.3%), were higher in the AFI < 5 cm group.

Conclusion: It is concluded that low AFI (<5 cm) in pregnancies complicated by PPROM is associated with a higher risk of adverse perinatal and maternal outcomes. Regular AFI monitoring can assist in timely decision-making, guiding delivery planning, and improving neonatal survival and maternal safety.

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