Abstract
Postoperative patients admitted to Intensive Care Units (ICU) and Coronary Care Units (CCU) are highly susceptible to hemodynamic instability, which often results in preventable complications and delayed recovery. Although monitoring technologies have advanced considerably, inconsistencies in nurse-driven interventions continue to influence patient outcomes. Implementing evidence-based nursing bundles that standardize hemodynamic management has the potential to improve clinical stability and promote faster recovery, yet their comprehensive impact on postoperative populations remains insufficiently explored. This study aims to evaluate the effectiveness of a nurse-led, evidence-based hemodynamic management bundle in improving physiological stability, reducing complication rates, and enhancing recovery outcomes among postoperative patients in ICU and CCU settings. A prospective, controlled interventional design will be employed in surgical and cardiac critical care units of a tertiary hospital, enrolling approximately 200 adult postoperative patients. Participants will be divided into two groups: one receiving the evidence-based nursing bundle and the other standard care. The intervention includes structured nurse-led protocols for fluid optimization, vasopressor titration, early mobilization, sedation and delirium prevention, glycemic regulation, and infection prevention. Primary outcomes will include hemodynamic stability indicators such as mean arterial pressure, heart rate variability, and oxygen saturation within target ranges, while secondary outcomes will assess complication rates and recovery parameters, including time to extubation, ICU/CCU length of stay, and 28-day mortality. Statistical analysis will utilize mixed-effects regression and survival models adjusting for baseline characteristics. It is anticipated that the evidence-based nursing bundle will enhance hemodynamic stability, reduce complications, and shorten recovery time, ultimately supporting the integration of such standardized interventions into critical care practice guidelines.