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Abstract
Objective: To compare the efficacy of Ondansetron and ketamine on post-spinal anesthesia shivering in cesarean section.
Methods: In this randomized controlled trial, we included 120 patients who underwent elective cesarean section under spinal anesthesia in Services Hospital, Lahore. The study was conducted from September 2024 to February 2025. The parturients were randomly assigned to two groups: one receiving ondansetron (Group 1) and the other receiving Ketamine at a dose of 0.25 mg/kg (Group 2). Frequency and severity of shivering was noted for each patient.
Results: The average age of patients was 30.7±5.4 years. The average body mass index (BMI) was 26.2±3.6 Kg/m2. Shivering occurred in 9 individuals (15.0%) from Group O and in 7 individuals (11.7%) from Group K, with a p-value of 0.59. Additionally, when evaluating shivering severity, 5 participants (8.3%) in Group O and 2 participants (3.3%) in Group K exhibited Grade I shivering, while 4 participants (6.7%) in Group O and 5 participants (8.3%) in Group K reported Grade II shivering (p-value 0.48).
Conclusion: Both ondansetron and ketamine are equally effective for preventing shivering in patients undergoing cesarean section under spinal anesthesia.